Pfizer Viagra Information
Viagra was the first prescription drug approved for the treatment of erectile dysfunction.
Viagra has since been approved by regulatory authorities in over 100 countries around the world. In the past four years, Pfizer Inc. has sold enough sildenafil citrate, brand named Viagra, to fill 100 million prescriptions for some 20 million patients worldwide, making Viagra one the most prescribed drugs in the world.
Why men prefer Viagra for erection enhancement:
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96% of men were satisfied with how well Viagra improved their erections in a 4-year, Viagra study. Viagra has continued to enhance their erections for four plus years.
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The cardiovascular safety of Viagra has been proven in tests involving thousands of patients.
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The majority of men who use Viagra had an enhanced erection within 20 minutes. One third of men had an improved erection in less than 14 minutes.
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In order for Viagra to enhance erections, Viagra requires stimulation, hence, no spontaneous erections.
Fortunately, there is now a proven way to treat erectile dysfunction and enhance erections. Viagra has been tested in over 130 studies involving men of all ages. In all of these clinical trials Viagra as proven to be the most trusted treatment option for erectile dysfunction.
Additional Pfizer Viagra Erectile Dysfunction Drug Information
The following topics concerning the use of Viagra represent the most commonly asked questions concerning the Pfizer Viagra for the treatment of erectile dysfunction. The following Pfizer Viagra information has been compiled from a variety of resources in order to give men an overview of the use of Viagra in treating erectile dysfunction.
What is Pfizer Viagra?
Viagra is the first oral medication for the treatment of erectile dysfunction. Viagra was originally developed as a cardiovascular medicine designed to improve blood flow in the vessels of the heart. However, during initial studies Viagra was found to have a pronounced side effect. Men began to report a remarkable difference in their ability to achieve and/or maintain an erection. Further studies were completed by Pfizer Pharmaceuticals and Viagra was subsequently approved for the treatment of erectile dysfunction. Pfizer Viagra® has change the course of erectile dysfunction treatment. Doctors, as well as, patients were so enthusiastic about the erectile dysfunction treatment drug. In the first six months alone, Pfizer's sales of Viagra, the blue diamond shaped tablet, topped 50 million. Pfizer Viagra® is dispensed as a pill and ingested orally. Approximately 30-60 minutes later Viagra is absorbed into the bloodstream and begins to significantly enhance erections.
What Pfizer Viagra clinical studies have been done?
Pfizer Viagra was administered to more than 3000 patients (age 19-87 years) with (ED) of various etiologies (organic, psychogenic or mixed) with a mean duration of 5 years. Pfizer Viagra demonstrated statistically significant improvement as compared to a placebo in all studies. In one particular study concerning the frequency of successful penetration during sexual activity and maintaining erection after penetration, 83% of these patients reported an improved erection on Pfizer Viagra verses 12% on a placebo medication (sugar pill). More astonishing are the results of five year studies involving the use of Viagra. The following graph depicts how men rate the long term use of Viagra for the treatment of male impotence:
Viagra has proven to be effective in treating impotence symptoms for a long period of time. The above graph depicts how effective Viagra has been in treating impotence symptoms. In one Viagra clinical trial, men who have taken Viagra for a period of 3-4 years still report that they are 95% - 96% satisfied with the their enhanced erections secondary to the use of Viagra.
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What is the mechanism of action behind Pfizer Viagra ?
The physiologic mechanism of erection of the penis involves release of nitric oxide in the corpus cavernosum during sexual stimulation. Nitrous Oxide then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood. Viagra has no direct relaxant effect on isolated human corpus cavernosum, but enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 by Viagra causes increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum Please refer to the following diagram:
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Why is Pfizer Viagra sometimes referred to as sildenafil citrate?
Sildenafil citrate represents the generic name for Pfizer Viagra pronounced as sill-DEN-uh-fil citrate. The generic name is the drug's nonproprietary or chemical name, whereas, the brand name is the name a pharmaceutical company gives to a medication for marketing purposes. The Pharmaceutical company owns the patent on a brand name medication for several years before the generic version of a medication is released.
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What is the appropriate Pfizer Viagra dose?
The standard dose is Pfizer Viagra 50mg one hour prior to sexual activity. However, if you are older than age 65 or have a serious kidney or liver disease some doctors may recommend starting with the minimal Pfizer Viagra dose of 25mg. Pfizer Viagra should not be taken more than once per any 24-hour period and the total dose of Viagra should not exceed 100mg in any given twenty four hour period.
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What about Pfizer Viagra pill splitting?
Pfizer Viagra is manufactured in 25mg, 50mg and 100mg tablets. All of the doses of Viagra, 25mg, 50mg and 100mg tablets are priced identically. Therefore, physicians agree that since Viagra is a lifestyle medication individuals should purchase the Pfizer Viagra100mg tablets and then split the Viagra 100mg dose into two 50mg doses (the standard dose) for a significant cost savings.
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Should I use Pfizer Viagra if I have not had sexual intercourse in a long time?
Sexual activity can cause a strain on the cardiovascular system. If you have not had any physical activity or if you have any pre-existing medical conditions you should consult with your doctor prior to using Pfizer Viagra erectile dysfunction medication.
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For what types of Erectile Dysfunction is Pfizer Viagra proving to be especially effective?
Pfizer Viagra is showing optimal results in individuals who experience erectile dysfunction secondary to high levels of anxiety (performance anxiety) and individuals with mild erectile dysfunction.
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Is Pfizer Viagra less effective in treating erectile dysfunction that is secondary to certain underlying medical conditions?
More data concerning this topic is expected in the near future. Some initial data suggests that men, who have undergone radical prostatectomy (surgical removal of their prostate), using nerve-sparing procedures, are not achieving the same positive results with the Pfizer Viagra erectile dysfunction medication.
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Can the Pfizer Viagra be combined with other treatments for erectile dysfunction?
The use of such combined treatments is not recommended, since no studies have been done to access Pfizer Viagra's safety and effectiveness.
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What if the Pfizer Viagra does not produce the desired effects that I anticipated?
If the Pfizer Viagra does not produce the desired effects do not despair. Viagra is just one in many treatment options for erectile dysfunction.
For additional information concerning other erectile dysfunction treatment options (click here)
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How much time must surpass prior to Pfizer Viagra being effective?
Pfizer Viagra is rapidly absorbed into the bloodstream. Maximum observed plasma concentrations are reached within thirty to ninety minutes (median time 60 minutes) of oral dosing on an empty stomach.
Please Note: Pfizer Viagra is absorbed into the bloodstream quicker on an empty stomach. The fat in the diet will compete with Viagra to be absorbed into the bloodstream.
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What happens if there is no sexual stimulation following a dose Pfizer Viagra?
Pfizer Viagra is naturally eliminated from your body in a few short hours.
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What are the precautions/warnings concerning Pfizer Viagra ?
Men who are taking medicines that contain nitrates (Nitroglycerin) of any kind should not use Pfizer Viagra. Patients should not take Viagra even if you only take nitroglycerin medication occasionally. Combining the Pfizer Viagra with nitrates can result in dangerously low blood pressure resulting in a stroke or heart attack (see below). There is also a potential for cardiac risk during sexual activity in patients with preexisting cardiovascular disease. Therefore, Pfizer Viagra should not be used in men were sexual activity is inadvisable secondary to their underlying cardiovascular status. The use of Pfizer Viagra offers no protection against sexually transmitted diseases, including HIV. In case of Viagra overdose, call your physician immediately.
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Why is Pfizer Viagra absolutely contraindicated in individuals who are currently taking medications containing nitrates?
Pfizer Viagra has been shown to increase the hypotensive effects of nitrates to possibly life threatening levels. Therefore, individuals who are currently using nitrates in any form even intermittently should not take Viagra. Nitrates are available in many medications; sprays, ointments, skin patches, pastes, as well as, tablets dissolved in the mouth. Nitrates are also found in illicit drugs such as amyl nitrate or nitrite "Poppers". If you are unsure if you are currently taking nitrates please value your health and consult with your local doctor and/or pharmacist.
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Can I use Pfizer Viagra with other medications?
Yes, Pfizer Viagra is generally safe to use while on other medications, however some medicines may potentate the effects of Viagra. Therefore, one should inform their physician concerning all medications they are taking, including those medications acquired by a prescription, as well as, over the counter medicines. Note Viagra does have one absolute contraindication; individuals who are taking medications containing nitrates (even intermittently) should not take Viagra.
Conclusions About Pfizer Viagra
Viagra has proven to be an effective erectile dysfunction treatment. For the last 6-7 years literally millions of men have trusted Viagra. Incredibly, some 9 Viagra tablets are dispensed every minute to men wanting enhanced erections across the globe.
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